B.A. in Biochemistry and聽B.A. in MCDB,聽University of Colorado - Boulder
NIH Pharmaceutical Biotechnology Trainee (2013 - 2015)
Plasticity in Recognition, lncRNA Biology
The emergence of聽myriad RNA sequences of unknown biological function begs the question of whether they form productive interactions within the cell. Given the prevalence and biological importance of DNA-binding transcription factors, I am particularly interested in plasticity at the DNA-binding interface and the mechanisms of RNA accommodation. I am taking an聽in vitro聽biochemical approach to explore the RNA-binding capacity of transcription factors and define the rules for RNA binding as it relates to regulation of transcription.
Other interests:聽When Nicholas isn鈥檛 in the lab, he spends most of his time rock climbing among the crags and high peaks of the Front Range.聽 He also loves crossword puzzles and vegetables.